Alpha Cognition Appoints Cedric O'Gorman, M.D., MBA as Chief Medical Officer
December 2, 2021
VANCOUVER, B.C., December 2, 2021. Alpha Cognition Inc. (TSX-V: ACOG)(OTCQB: ACOGF)(“Alpha Cognition”, or the “Company”), a biopharmaceutical company committed to developing novel therapies with the potential to transform the lives of people with debilitating neurodegenerative disorders, today announced the appointment of Cedric O’Gorman, M.D., as the Company’s Chief Medical Officer. Dr. O’Gorman will lead medical, clinical and regulatory functions in support of the company's clinical-stage products ALPHA-1062 and ALPHA-0602. Dr. O’Gorman will also serve as a member of the executive management team, reporting to the CEO.
Dr. O’Gorman brings to Alpha Cognition more than two decades of life sciences experience in clinical development, medical affairs and medical strategy, almost exclusively in the CNS therapeutic area, and across all stages of drug development. Prior to Alpha Cognition, he served as Senior Vice President, Clinical Development and Medical Affairs at Axsome Therapeutics where he led clinical development programs for therapeutic indications which included major depressive disorder, agitation associated with Alzheimer’s disease, narcolepsy, and migraine. Prior to Axsome, Dr. O’Gorman was Vice President of Medical Affairs at Intra-Cellular Therapies and before that, Dr. O’Gorman was the U.S. Medical Lead for Psychiatry at Genentech/Roche. Prior to Genentech/Roche, Dr. O'Gorman spent 5 years at Pfizer representing medical affairs on several branded neuroscience products for schizophrenia, bipolar disorder, and major depressive disorder.
Michael McFadden, CEO of the Company commented: “As a board-certified psychiatrist, Dr. O’Gorman’s addition to the management team provides critical support for the advancement of our clinical programs. His clinical vision and proven leadership, including his extensive CNS medical and research experience, further strengthens our clinical development efforts and support the progress of our product pipeline.”
Dr. O’Gorman additionally commented: "I am excited to be joining Alpha Cognition and look forward to working with the outstanding leadership team to progress the company's multiple programs toward later-stage clinical development, with the goal of getting safe and effective therapies to patients in medical need."
Dr. O'Gorman received his medical degree from the National University of Ireland in Galway, trained at the Institute of Psychiatry in London, England, and earned his Master of Business Administration from the New York University Stern School of Business.
About Alpha Cognition Inc.
Alpha Cognition Inc. is a clinical stage, biopharmaceutical company dedicated to developing treatments for under-served neurodegenerative diseases, such as Alzheimer's Dementia and Amyotrophic Lateral Sclerosis (ALS).
ALPHA-1062, is a patented new chemical entity that has demonstrated safety and improved tolerability in human clinical trials. It is being developed as a new generation acetylcholinesterase inhibitor for the treatment of Alzheimer's disease, with minimal gastrointestinal side effects and novel routes of administration. ALPHA-1062's active metabolites are differentiated from donepezil and rivastigmine in that they may sensitize neuronal nicotinic receptors, most notably the alpha-7 subtype, which is known to have a positive effect on cognition. ALPHA-1062 is also being developed in combination with memantine to treat moderate to severe Alzheimer's dementia and in a nasal spray formulation to treat traumatic brain injury.
ALPHA-0602 (Progranulin) is expressed in several cell types in the central nervous system and in peripheral tissues, regulates cell survival and certain inflammatory processes, and plays a major role in regulating lysosomal function and microglial responses to disease. Its use for the treatment of neurodegenerative diseases has been patented by the Company and granted an Orphan Drug Designation.
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